houston nutt peter marshall peter marshall zombie boy zombie boy harvard yale joe paterno lung cancer
Monday, April 30, 2012
America Admits to Targeted Drone Killing for the First Time Ever [Drones]
black friday violence il postino il postino online black friday deals college football scores maggie daley black friday online deals
Wednesday, April 18, 2012
New Android users in India offered 1GB of free data, courtesy of Google and Reliance
In an effort to stir the interest for Android smartphones in India -- and, to let new customers test drive its 3G network -- the carrier Reliance Communications has partnered with Google to provide 1GB of data usage for all new activations of CDMA Android handsets. The promotion is available to both pre-paid and postpaid customers, who may take advantage of the deal now through June 15th. Once aboard, subscribers will have 30 days to burn through their allotment and discover the joys of a smartphone. Additionally, the carrier will extend a similar offer for new GSM Android activations, which is set to begin on May 5th. Reliance plans to drive its promotion with an ad campaign that sports an Android bot in the carrier's colors -- though, we're still partial to green. Just sayin'.
New Android users in India offered 1GB of free data, courtesy of Google and Reliance originally appeared on Engadget on Tue, 17 Apr 2012 10:19:00 EDT. Please see our terms for use of feeds.
Permalink | | Email this | Commentsgifts for mom pepper spray storage auctions storage auctions les miles les miles beyonce dance for you video
Friday, April 6, 2012
Commercial Real Estate By State - Free Article Directory
Posted by BeauleKeiter426 , On April 6, 2012 , in Gaming , Comments Off
This industrial real estate investment business enterprise is definitely picking up, and from now on are sometimes an excellent time and energy to expend. In 2004, rates with industrial properties increased significantly ? twenty six per-cent intended for condo things, twenty one per-cent with regard to commercial qualities, 18 percentage for list qualities and also half dozen percentage with regard to business office architectural structures.. If you feel business real estate property will be something you actually may not execute, I might need to express you are significantly erroneous. That has a little awareness plus ample inspiration, any one can easily achieve this business. The results much outweigh the costs, and often create a living of which many wish, although in no way in fact practical knowledge.
The initial step to purchasing industrial real estate knows that which you are shopping for. Private property refers to just about any actual house, not including a new residing, or property using you to definitely some home items useful for housing reasons. The particular time period ?commercial serious estate?" involves (yet isn?t limited by) qualities useful for industrial, private, medical as well as educational applications, as well as qualities along with four or higher models for household functions. Within professional real-estate, your own economic investment decision is quite reduced, perhaps even non-existent. Acquire house having 100% of other people?s capital (OPM), as well as create large revenue yourself. This is actually the just sector in which there are actually virtually poisonous with $ $ $ $ just waiting being assimilated! Look for the money and obtain to making an investment!
A reliable business real estate agents are specially prepared to deal with professional real estate property deals which have been completely different through typical housing offers. An expert professional real estate property specialist also can reveal perfect commercial real estate investment which can be on the market. Institutional plus exclusive people typically ?secretly? sell off away from aspects of their particular commercial residence portfolios, and a commercial residence agent could allow you to inside during this insider details. It will require a similar degree of be employed by each and every professional real estate option, indicating you must feel the similar processes when. Why not improve the result and buy the larger returning offers, rather than the small models? Synergy is actually a key term around business real estate property, seeing that little alterations could provide substantial success.
Business oriented property can readily be described as a part-time job of which generates incremental income. Ceremony begin with part-time, and hold a position unless you want to have enough cashflow plus money in order that, finally, all you conduct will be business oriented property. Business oriented housing to be a full-time work helps you possess health improvements for example becoming your personal manager in addition to having the ability to work at home. You are able to generate your special business oriented property enterprise plus quickly create a solid web worth and favourable net income. Probably the most attracting benefit from commercial property is definitely benefit. Huge sales, the fact is, that may be created using a tiny level of energy. You can make precisely the same amount of cash quick resorting or marketing 100 single-family residences as you could produce having an individual business oriented property cope. The profits is usually astonishing!
Are you currently looking for even more on Property Agent Singapore? Go to Sam Q. Dixon?s web site now for a lot more data on Property Agents without delay.
harrison barnes bby brett ratner stevie nicks anchorman jennie garth capybara
Podcast Basics For Dundee MLM Business Bloggers | Elgin IL ...
Today?s Dundee direct selling article is for Dundee internet rookies who want to kick up their web marketing a notch by adding a podcast to their Dundee home business blog.
A podcast is a multimedia file that is downloaded for playback on a mobile device such as an iPod or laptop computer. It can be a digital recording of a radio program or, more often, a program produced solely for online distribution. A podcast can be a recording of a webcast: a live Dundee program that is ?streamed? or broadcast on the internet in real time. When this is the case, it is similar to a DVD recording of a live program that you store in the database of your playback device.
A related term is the acronym RSS which probably originally stood for Rich Site Summary feed but is sometimes used for Really Simple Syndication. You have probably seen the term RSS on websites. An RSS feed allows digital files to be downloaded in a standard format. Hanover Park podcast listeners often subscribe to favorite ongoing podcasts. When new podcasts are produced, they are automatically downloaded by RSS applications.
It is fairly simple hardware- and software-wise to product your own podcast for your Dundee online business. Your laptop may already have recording capability. If not, you can buy any equipment you need in the Hanover Park area.
Dundee business owners operating on a shoestring will be happy to know that basic recording and editing software can be downloaded for free. If you want to get fancy, you can always buy more sophisticated software at Illinois specialty computer stores. I recommend using a headset microphone so the mic is always in the right spot to get a clear and consistent recording.
Now the fun part: what will you podcast? The possibilities are endless for Dundee direct marketers. You can record Illinois trade show presentations, interviews with founding distributors of your Dundee direct sales company, or create an entertaining pitch about your Hanover Park business opportunity. Let your expertise and enthusiasm shine.
Creating a podcast gives you a chance to connect with potential Dundee customers or downline members in a personal way.
I am Probiotic Cacao Distributor Adam Paul Green, a network marketer representing Xocai Nuggets. I am based in Elgin, Illinois.
Are you interested in owning a Xocai Nuggets online business? My team members are steadily expanding their networks and increasing their direct sales income.
Call me today to start building your own online Xocai Nuggets business!
Probiotic Cacao Distributor Adam Paul Green
Elgin, Illinois zip code 60123
801.437.5994 401adampaulgreen@adampaulgreen.com
Xocai Nuggets residual income opportunity for Dundee home-based business owners.
Join Winner?s Circle today!
I am Adam Paul Green, and I am a Elgin-based Xocai artisan chocolate distributor. I joined Xocai in May 2006. I sell the industry-leading Xocai Nuggets and Xe Energy Drink online and in Elgin, Dundee, Carpentersville, and Streamwood. Our valued Hanover Park customers recommend Xe Energy Drink because Xe Energy Drink joseph schmidt chocolate will change your life!.
Winner?s Circle is also a fantastic Xocai Nuggets home-based business within 35 miles of the Hanover Park area. Illinois entrepreneurs can supplement their income by cashing in on a high-demand Illinois healthy artisan chocolate market. To learn more about Winner?s Circle, visit http://adampaulgreen.com/videos/.
Call me at 801.437.5994 to own your own Xocai Nuggets business in Elgin, Dundee, Carpentersville, or Streamwood.
The URL for my personal Hanover Park Xocai chocolate web page in Elgin, Illinois 60123 is http://adampaulgreen.com/videos/. The URL for another one of my 35 Illinois Xocai artisan chocolate web pages is http://adampaulgreen.com/resources/. I also have a Illinois healthy chocolate page at http://adampaulgreen.com/product/.
jack dempsey lake malawi warren jeffs phaedra parks oklahoma earthquake earthquake today earthquake today
Thursday, April 5, 2012
Pregnenolone Anti-ageing Aid To Beat Stress And Boost Mind Power
Pregnenolone is a powerful hormone which is present naturally in the body and is responsible for nearly all of the body?s steroid hormone production during the cellular growth process powered by mitochondria. Pregnenolone is therefore also popularly referred to as the mother of all steroid hormones in the body.
As pregnenolone plays a pivotal role in the production of all vital steroid hormones in the body such as progesterone, estrogen, testosterone, dhea, etc. prenenolone is indirectly responsible for the production of all these essential hormones in the body. Produced in the adrenal glands, pregnenolone is therefore endowed with powerful anti-inflammatory arthritis pain relieving properties.
Pregnenolone was first discovered and formulated in the 1940s when it was first given to factory workers to improve their performance.
It was found to reduce the stress levels of the workers while acting as a pain reliever for arthritis pain and inflammation as well. However, due to the discovery of another vital steroid hormone during that time, pregnenolone lost its value and significance.The interest in pregnenolone as an anti ageing supplement and anti inflammatory drug was rekindled in the 1990s. It is today increasingly used as an anti aging memory enhancer and an aid to boost memory. As a mind power aid, pregenenolone benefits mental health and wellbeing as part of the complex steroid hormone production process.
Thus while pregnenole benefits had been established as anti inflammatory and anti depressant to relive stress, pain and inflammation related to arthritis, injury and other bodily conditions, in the recent times pregnenolone supplementation also entered the anti aging arena to address mental decline and memory loss, and act as a memory enhancer.
Pregnenolone therapy has thus come in line with other cognitive enhancers such as Idebenone, piracetam, Hydergine and Vitamin B12 to combat stress and boost memory. As pregnenolone levels are known to decrease overtime, with 60 percent decline in pregnenolne levels by the time one reaches the age of 70, it is suggested one take pregnenolone supplements to prevent physical and mental decline associated with old age.
It has also been proved to be extremely beneficial for menopausal women as it offers a natural estrogen therapy and a way to increase estrogen. A pregnenolone supplement is available in tablet form and as a pregnenolone cream. As a natural supplement, Pregnenolone is safe to use and presents few side effects.
shamrock slainte the quiet man yellow cab dropkick murphys guernsey nit
NC Industrial Commission to review workers comp ... - Car Insurance
The N.C. Industrial Commission said Monday it would launch a review of its policies and procedures to ensure workers who are injured on the job are protected from reckless employers.
Acknowledging problems in the state?s workers? compensation system, commission Chairwoman Pam Young said her agency would work with the state Attorney General?s office ?to examine overall strategies and enforcement.?
?We will continue to meet with stakeholders on this very important issue, and, as we always have, the commission will continuously review its operations to make certain they are as efficient and effective as possible,? she said in a statement.
The move comes in response to a News & Observer investigation Sunday that revealed that tens of thousands of North Carolina businesses don?t buy workers? compensation insurance, putting their employees at risk and violating state law.
The state doesn?t track whether employers buy the insurance coverage ? even though the Industrial Commission is notified when an employer lapses ? and often only learns about noncompliant companies when a worker gets hurt and appeals for help. Likewise, the commission typically doesn?t enforce fines ? up to $100 per day without coverage ? and few of those referred for prosecution lead to an arrest or criminal charges.
Young, who former Democratic Gov. Mike Easley appointed to the commission in 2007, refused to comment directly about the problems identified in the investigation. Her statement also doesn?t give specifics about the commission?s review.
?The North Carolina workers? compensation system faces many challenges, including ensuring that employers are providing the necessary and adequate coverage for their employees,? she said. ?The best way for our system to be strong and vibrant is to be sure all participants meet their obligations.?
Democratic Gov. Bev Perdue, who has appointed members of the commission, declined to comment, deferring to Young?s statement.
House Speaker Thom Tillis and Senate leader Phil Berger, both Republicans, could not be reached for comment.
?Start at the top?
Republican state Sen. Harry Brown put the problems raised on Perdue?s doorstep. ?I think it?s got to start at the top,? he said. ?I think the governor and commissioners themselves have that (enforcement) power and for whatever reason they?ve chosen not to do it.?
But Brown, an automobile dealer who pays for the insurance, said he sympathizes with small businesses who can?t afford the insurance.
Democratic state Sen. Doug Berger, a former deputy commissioner who handled noncompliant cases, wants the governor to make prompt reforms. ?I?m going to ask the governor to put some reforms in the budget bill for this session,? he said.
In addition, he wants to see legislation requiring the commission?s investigators to do spot checks to see whether businesses are complying with the law.
An N&O analysis of a state database indicates that insurance carriers cover about 140,000 businesses even though the state counts roughly 170,000 companies in the state. Businesses with three or more employees are required to buy insurance or certify with the state that they can cover the cost of employees? injuries. In fiscal year 2011, the commission dealt with 62,409 workers? compensation claims.
Berger said one other possible solution is giving the state Department of Insurance the power to investigate workers? compensation fraud. ?Let?s put these investigations in the hands of people who do this and know how to manage it,? he said.
Last week, Insurance Commissioner Wayne Goodwin, a Democrat, said he would be willing to take over workers compensation fraud investigations if the legislature directed him to and gave him the resources.
?A right to be protected?
Few other lawmakers and candidates offered concrete solutions. House Speaker Pro Tem Dale Folwell, a Winston-Salem Republican, said the investigation illuminates a need for more reform of the workers comp system and pledged to call together people stakeholders to talk about possible solutions.
Folwell, who is running for lieutenant governor, helped lead an effort in the state legislature last year to rewrite parts of the workers? compensation law. But the changes curtailed the amount of payments businesses must make to injured workers and did not address employers who don?t buy insurance.
A number of the candidates for governor said protecting workers is vital, including a spokesman for Republican Pat McCrory who said ?there certainly must be a safety net in place for workers who are injured.?
In a statement, Democrat Bob Etheridge said ?the law must be enforced? because employees ?have a right to be protected on the job.?
His challenger, state Rep. Bill Faison, echoed the sentiment, saying ?when people are hurt on the job they need all the help they can get.?
david archuleta hobbit trailer greenhill nj plane crash plane crash new jersey beef o bradys bowl the hobbit
google offers cerebral palsy death clock death clock stanley tucci stanley tucci x factor voting
Hold the Cheese! | Food & Drink | Atlantic City Weekly
Burger.org, a Glatt Kosher upscale burger joint to debut soon in Margate. ?
Future looks bright for burger.org in Margate
Upscale burgers are certainly not a new concept, either in our region or throughout the country.?
Neither is Glatt Kosher food, with now four local restaurants ? year-round Jerusalem and Bubbie?s Bistro, plus seasonal Shalom Pita ? serving food adhering to those religious tenets.?
What is unusual, perhaps even shocking to some, is the combination of those two.?
That idea finds fruition later this month with the Margate opening of Burger.org near the corner of Jerome and Ventnor avenues.?
For proprietors Eyal Aranya and Yoni Nadav, this shore eatery represents the third location of their unique food provider.?
Aranya tells us that they had originally intended to create a Philly place featuring organic, grass-fed beef and other naturally-raised meats.?
That initial entry, at 326 South St., opened in May of 2010.?
After a few short months, the pair opted to tweak their format.?
Explaining that both men, natives of Israel, share ?a traditional religious history,? Aranya goes on to add that family members encouraged them to consider becoming a Kosher facility.?
Contacting an organization called Community Kosher of Greater Philadelphia ? which Eyal characterizes as ?a Supreme Court? comprised of five Rabbis ? Burger.org became Glatt certified in August 2010.?
Since that time, they?ve gone on to open a second location last June on Chestnut Street near Rittenhouse Square.?
And once this Margate location is up and running later this month, the ambitious partners have a fourth place already in the works, slated for the Ellisburg Circle in Cherry Hill.?
As for the Burger.org concept, it?s admirably straightforward and targeted ?not only for the Jewish community, everyone is welcome here.??
Various meats are available: beef, of course, but also turkey, lamb, chicken, fish and a house-made veggie burger composed of spinach, corn, carrots, peas and cucumber.?
Beef is an 80/20 mix of chuck, always ground daily according to strict rabbinical guidelines, in each store. All bread products, including their rolls, must also baked on premises.?
A quartet of special burgers includes that veggie option, along with El Mariachi, adding jalapenos, pico de gallo and guacamole; El Gringo, topped by mushrooms, fried egg and pastrami and El Dorado, with the unusual addition of hummus, mushrooms and eggplant.?
We don?t know about you, but a burger with fried egg and grilled pastrami sounds too good to be missed.?
Menu options for those not burger-inclined will also available.?
Like wings, grilled or fried, plus sandwiches including steak, chicken breast, fried chicken schnitzel or the aforementioned pastrami.?
*/ var formWrap = $( 'add_comment_form' ); var formDivs = $$( '#add_comment_form div' ); for ( i = 0; i ' + name + ' said... on ' + timeStamp }); var commentPar = new Element( 'p', { 'html': '?' + comment + '?' }); var ruleDiv = new Element( 'div', { 'class': 'rule' }); authorPar.inject( commentDiv ); commentPar.inject( commentDiv ); commentDiv.inject( commentWrap ); ruleDiv.inject( commentWrap ); } else { msgPar.innerHTML = "Comment has been sent for approval"; } } } // FUNCTION TO DISPLAY LATEST COMMENT ON MULTIMEDIA PAGES TRIGGERED BY AJAX CALL BACK function showMMComment(theName, theComment) { // 'name' and 'comment' have placeholder content for testing, actual data would be sent from DB var name = theName; var comment = theComment; var flagged = false; var status; var error; /* COMMENT HTML MARKUP STRUCTURETheDude said...
Mandy Moore is pretty smokin. I wish I was cool enough to date her. Does anybody know how I can get her number?
' + comment }); numDiv.inject( commentLi ); commentPar.inject( commentLi ); commentLi.inject( commentUl ); } else { msgPar.set( 'html', 'Comment has been sent for approval' ); } } } function displayNewComment() { var msgP = document.getElementById("msg"); msgP.innerHTML = "Thank you for your submission. Your comment has been added below."; if(comment != "") { if(!flagged) { var commentSection = document.getElementById("ajaxSection"); var commentDiv = document.createElement("div"); var timeStamp = 'Apr 5, 2012 at 05:29AM'; commentDiv.innerHTML = ''; commentSection.appendChild(commentDiv); } } } function validateCommentForm(form){ var fieldEmail = document.getElementById("field.email"); var fieldName = document.getElementById("field.name"); var nameValue = fieldName.value; var emailValue = fieldEmail.value; var filter = /^([a-zA-Z0-9_\.\-])+\@(([a-zA-Z0-9\-])+\.)+([a-zA-Z0-9]{2,4})+$/; if (filter.test(emailValue)) { var fieldBody = document.getElementById("field.body") var bodyValue = fieldBody.value; bodyValue = bodyValue.replace(/&/g,"&"); bodyValue = bodyValue.replace(/,"/g,">"); bodyValue = bodyValue.replace(/\r\n/g,"
"); bodyValue = bodyValue.replace(/\n/g,"
"); bodyValue = bodyValue.replace(/\r/g,"
"); fieldBody.value = bodyValue; if(navigator.appName == 'Microsoft Internet Explorer') { if(document.getElementById('submit').disabled) { document.getElementById('submit').disabled=false; } else { document.getElementById('submit').disabled=true; } } return insertComment(form,true,function(){return showEditorialComment(nameValue, bodyValue)}); } else { alert('Please enter a valid Email below.'); form.elements[field.email].focus(); return false; } }
pecan pie the hobbit trailer red velvet cake recipe josh krajcik porphyria cinnamon rolls krampus
Man in court over cat-swinging
[ [ [['beyond the incredible personal tragedy', 3]], 'http://news.yahoo.com/stand-ground-laws-not-just-gop-policy-records-053103956.html', '[Related: \?Stand your ground\? laws not just GOP policy\, records show]', ' ', '630', ' ', ' ', ], [ [['A JetBlue flight from New York to Las Vegas', 3]], 'http://yhoo.it/GV9zpj', '[Related: View photos of the JetBlue plane in Amarillo]', ' ', '630', ' ', ' ', ], [ [['I went out on to my porch and heard a bang', 6]], 'http://news.yahoo.com/photos/dozens-killed-in-russian-plane-crash-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/b/87/b870130db8e1341aaa3e3f4a2aefcfcd.jpeg', '500', ' ', '(AP Photo/Russian Ministry of Emergency Situations press service)', ], [ [['Afghan security forces and police killed three', 3]], 'http://yhoo.it/H9BcJE', '[Related: Bales\' wife on his alleged shooting: \'He would not do that\']', ' ', '630', ' ', ' ', ], [ [['looking for fireworks between the opposing camps', 16]], 'http://yhoo.it/GSvEsj', '[RELATED:\?It?s going to be a circus\?: Activists begin protests outside Supreme Court]', ' ', '630', ' ', ' ', ], [ [['entirely respectable way to put off the searing constitutional controversy', 8]], 'http://yhoo.it/GE6jSh', '[RELATED: Obama\?s health care law passed 2 years ago, but where are we now\?]', ' ', '630', ' ', ' ', ], [ [['Witnesses said the gunman pulled up on a black scooter', 7]], 'http://yhoo.it/GzwOIW', '[Related: New York police tighten security at Jewish sites]', ' ', '630', ' ', ' ', ], [ [['test Zimmerman for alcohol or drugs', 11]], 'http://yhoo.it/Gzn6VF', '[Related: White House says Trayvon Martin is local issue]', ' ', '630', ' ', ' ', ], [ [['Oikos University', 8]], 'http://news.yahoo.com/photos/deadly-oakland-university-shooting-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120402/shooting.jpg', '450', ' ', 'REUTERS/Reuters TV/KNTV/Handout', ], [ [['Trayvon Martin decked the Neighborhood', 7]], 'http://yhoo.it/GUovUP', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/2/61/261d2c36bccf0971c2734a4d4398aa5a.jpeg', '512', ' ', 'AP/David Goldman', ], [ [['Can you create commerce in order to regulate it', 9]], 'http://yhoo.it/GSgtu8', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/7/78/778e2416573870cd705774e92403447d.jpeg', '630', ' ', 'AP/Charles Dharapak', ], [ [['associated with such a small earthquake', 4]], 'http://yhoo.it/GTco9z', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/0/b4/0b493c1a47b6e3f97f8f48a2b251d7d4.jpeg', '630', ' ', 'AP Photo/Carrie Antlfinger', ], [ [['Fox News host Geraldo Rivera sparked outrage', 3]], 'http://yhoo.it/GKMVTk', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/2/7c/27c7367bc512d233ae1790b320a5e92c.jpeg', '630', ' ', 'AP Photo/John Minchillo', ], [ [['The charges signed against Bales include', 1]], 'http://yhoo.it/wZT5zV', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/7/a0/7a07c51b2aa0f39b1a23355046d13870.jpeg', '512', ' ', 'AP Photo/DVIDS\, Spc\. Ryan Hallock\, File', ], [ [['George Zimmerman, if I had a son', 6]], 'http://news.yahoo.com/photos/thousands-protest-fla-teen-death-1332387124-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/os/152/2012/03/22/d761a49f3fcc99080a0f6a70670053cd-jpg_150905.jpg', '500', ' ', 'AP Photo/John Minchillo', ], [ [['xxxxxxxxxxxx', 11]], 'http://news.yahoo.com/photos/russian-grannies-win-bid-to-sing-at-eurovision-1331223625-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/1/56/156d92f2760dcd3e75bcd649a8b85fcf.jpeg', '500', ' ', 'AP', ] ]
[ [ [['because I know God protects me', 14], ['Brian Snow was at a nearby credit union', 5]], '28811216', '0' ], [ [['The state news agency RIA-Novosti quoted Rosaviatsiya', 6]], '28805461', '0' ], [ [['measure all but certain to fail in the face of bipartisan', 4]], '28771014', '0' ], [ [['matter what you do in this case', 5]], '28759848', '0' ], [ [['presume laws are constitutional', 7]], '28747556', '0' ], [ [['has destroyed 15 to 25 houses', 7]], '28744868', '0' ], [ [['short answer is yes', 7]], '28746030', '0' ], [ [['opportunity to tell the real story', 7]], '28731764', '0' ], [ [['entirely respectable way to put off the searing constitutional controversy', 7]], '28723797', '0' ], [ [['point of my campaign is that big ideas matter', 9]], '28712293', '0' ], [ [['As the standoff dragged into a second day', 7]], '28687424', '0' ], [ [['French police stepped up the search', 17]], '28667224', '0' ], [ [['Seeking to elevate his candidacy back to a general', 8]], '28660934', '0' ], [ [['The tragic story of Trayvon Martin', 4]], '28647343', '0' ], [ [['Karzai will get a chance soon to express', 8]], '28630306', '0' ], [ [['powerful storms stretching', 8]], '28493546', '0' ], [ [['basic norm that death is private', 6]], '28413590', '0' ], [ [['songwriter also saw a surge in sales for her debut album', 6]], '28413590', '1', 'Watch music videos from Whitney Houston ', 'on Yahoo! Music', 'http://music.yahoo.com' ], [ [['keyword', 99999999999999999999999]], 'videoID', '1', 'overwrite-pre-description', 'overwrite-link-string', 'overwrite-link-url' ] ]
news channel 4 whitney houston autopsy dobie gray bruce springsteen grammy nominations lil boosie bobbi kristina brown
LG LS831 goes back to FCC, reveals 5MP camera, Sprint intentions
LG LS831 goes back to FCC, reveals 5MP camera, Sprint intentions originally appeared on Engadget on Tue, 03 Apr 2012 12:34:00 EDT. Please see our terms for use of feeds.
Permalink | | Email this | Commentscolton harris moore hurd hurd christopher hitchens ron paul 2012 zynga stock zynga stock
Wednesday, April 4, 2012
OMGPOP?s Draw Something Surpasses 50 Million Downloads
oregon ducks oregon football lana turner donald glover julio cesar chavez jr jason segel turducken
Tuesday, April 3, 2012
Death cap mushroom poison to arrest pancreatic cancer in mice
The mere thought of an identification error sends a chill down the spine of any mushroom lover: The death cap mushroom (Amanita phalloides), which resembles the common white button mushroom, contains one of the most deadly poisons found in nature, ?-amanitin. This substance kills any cell without exception, whether it be healthy or cancerous. At the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the National Center for Tumor Diseases Heidelberg, immunologist Dr. Gerhard Moldenhauer, jointly with biochemist Professor Dr. Heinz Faulstich, Max Planck Institute for Medical Research, has now developed a method for destroying cancer cells using the dreaded fungal toxin without harming the body.
The trick to accomplish this is to deliver the poison directly to the right address in the body using something that virtually serves as a cab. In this case, the cab is an antibody whose highly specific arms attach to a cancer-typical cellular surface protein called EpCAM. The fungal toxin is linked to the antibody in a stable chemical conjugation.
In the culture dish, the poison-loaded antibody arrested the growth of pancreatic, colorectal, breast and bile duct cancer cell lines. In mice bearing transplanted human pancreatic cancer, a single antibody injection was sufficient to inhibit tumor growth. Two injections of higher doses of the antibody even caused complete tumor regression in 90 percent of the animals. Even the higher doses did not cause any poison-related damage to the liver or other organs of the animals.
EpCAM, the protein chosen by the Heidelberg immunologists as the tumor cell recognition structure, is a characteristic membrane protein of epithelial cells. This type of cells lines all inner and outer surfaces of the body. Most malignant tumors originate from such epithelial tissues. Many of these, such as pancreatic cancer, breast and ovarian cancers, bile duct carcinomas and tumors of the head and neck, produce too much EpCAM ? and this is frequently associated with an extremely poor prognosis of the disease. EpCAM is therefore considered a suitable target structure for attacking tumor cells.
"Treatments with unconjugated antibodies against EpCAM have already been tested in clinical trials such as for breast cancer. They were intended to attack the cancer solely with the weapons of the immune system, but they turned out to be clinically ineffective," said Gerhard Moldenhauer. "However, our amanitin-conjugated antibody has a much greater potential for killing cancer cells."
Details are of vital importance
Each antibody is linked to between four and eight toxin molecules. Amanitin is regarded as very suitable for this purpose. It is small enough not to be recognized as foreign by immune cells, while it is also robust enough to lend itself to chemical conjugation. "When developing toxin-conjugated antibodies you have to take an awful lot of things into account," Moldenhauer explains. "The cancer cell has to regularly take the target molecule including the attached antibody into its interior, for this is the only place where the poison can act. In the cell's interior, the poison needs to detach from the antibody or else it will not be effective. At the same time it is absolutely vital that it does not get lost while it is being carried through the body, because this could cause severe adverse side effects."
The dosage of the amanitin antibody needs to be determined with the utmost care. One problem is that liver cells are extremely sensitive to the fungal toxin; another is that other healthy cells carry the EpCAM molecule as well and are therefore endangered. However, the results obtained in mice give reason to be optimistic, according to Gerhard Moldenhauer: "Even at high doses we have not detected any organ damage in the animals. We therefore expect that there is a sufficient therapeutic window for a dosage that kills cancer cells while leaving healthy tissue unaffected."
Moldenhauer, who has many years of experience in developing therapeutic antibodies, already has plans for amanitin-conjugated guided missiles against other cancers. In particular, certain types of leukemia and lymphoma cells also carry highly specific surface molecules which lend themselves as target structures for poison-loaded antibodies.
###
Helmholtz Association of German Research Centres: http://www.helmholtz.de/en/index.html
Thanks to Helmholtz Association of German Research Centres for this article.
This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.
This press release has been viewed 27 time(s).
corso james arthur ray james arthur ray elisabeth shue avastin avastin robert wagner
Video: Cheney returns home after heart surgery
The former Vice President was released from a Virginia hospital after receiving a heart transplant. NBC?s Brian Williams reports.
>>> we have a quick update on former vice president dick cheney . he's back home tonight , released earlier today from a virginia hospital, just ten days after receiving a heart transplant from an anonymous donor. cheney, who is seen here with his wife lynn is 71 years old. this photo showing the fit mr. cheney was put out on twitter today by daughter liz cheney .
judy garland j r martinez j r martinez long island serial killer wizard of oz jeff green saturday night live
Monday, April 2, 2012
Twitter for BlackBerry 3.0 brings easier photo-uploading, automatic link-shortening, BBM integration
Twitter for BlackBerry 3.0 brings easier photo-uploading, automatic link-shortening, BBM integration originally appeared on Engadget on Mon, 02 Apr 2012 19:04:00 EDT. Please see our terms for use of feeds.
Permalink | | Email this | Commentstoure patti smith lottery winners lottery winners april fools day pranks ohio state vs kansas daniel von bargen
Pinnacle Airlines files for bankruptcy - Financial News
(Reuters) - Pinnacle Airlines Corp said late on Sunday it filed for bankruptcy protection to resolve its operational and financial difficulties and implement a turnaround plan.
The regional airline said it has received a commitment for $74.3 million of debtor-in-possession (DIP) financing from Delta Air Lines .
As part of the bankruptcy plan, Pinnacle said it would restructure its key operating agreements with Delta Air lines and would wind down its operations with United Airlines .
The company said it would also look to achieve cost savings from its workforce but did not provide further details in its statement.
Pinnacle had listed estimated assets and liabilities above $1 billion, according to a court filing.
In the past, United Continental Holdings Inc's United Airlines and Delta Air Lines Inc have taken the Chapter 11 route to cut costs and later found merger partners.
In November, AMR Corp , the parent of American Airlines, also filed for bankruptcy.
The case is Pinnacle Airlines Corp, Case No. 12-11343, U.S. Bankruptcy Court, Southern District of New York.
(Reporting by Sakthi Prasad in Bangalore; Editing by Michael Perry)
jetblue michelle malkin october baby sugarland 16 and pregnant ludwig mies van der rohe jamie lynn sigler
Car Upholstery Repair | Automotive Tips
Whether you need to repair your car upholstery because you want to restore a classic car, or because the interior of your car is just very ratty, you may need a little guidance if you don?t know what you are doing. The upholstery in older cars in particular were installed with the assumption that they would last for a long time, but that is not always the case. Even newer cars may need their upholstery repaired because of accidents that happen within the interior of the car.
Repairing the upholstery in your car interior may also be harder to do if you are not sure what kind of materials you are working with. The right tools may also be needed to remove, repair and install new upholstery into the car, and may be a hefty investment in itself. Sometimes, it may simply be wiser to have a professional do the job for you, but when there isn?t one in your area, a little do-it-yourself skills may prove to be useful.
Getting Started: Repairing Your Car Upholstery
?Before even getting started on the upholstery in your car, you should first gauge the kind, as well as the amount of work that needs to be done. A proper evaluation will also help you determine the total amount of money you will need to spend on the entire repair job, allowing you to plan your expenses and total work accordingly.
?Here are some things you should look for when inspecting your car upholstery for repairs:
- Seats ? Much of the upholstery found on your seats may need repairs because of constant use by passengers. If you constantly use your ride to transport large amounts of people around every day, then the car seats may experience a lot of wear and tear. Look for new seat covers made for your car model in particular, or have some custom made if stores do not carry any.
- Carpeting ? Since this is where people will step on as soon as they enter the car, your carpets may be the first piece of upholstery that needs repairing. Ready-made carpets are available in nearly every automotive store around, or you can also have them custom made to your own preferences.
- Dashboard ? Constant exposure to sunlight, UV rays, and even the stuff you put on the dashboard may wear out the upholstery that covers it. If you start to see prominent scuff marks, scratches and cracks, it might be a good idea to start repairing the upholstery. This may be one of the hardest places to perform repairs, however, even with aftermarket parts made specifically for your car?s dashboard.
- Headliner ? The upholstery on your headliner can be a lot like your car seats, but can be more expensive to install properly. You may even have to remove your windshield to perform a headliner repair, so try to get this done by a professional if funds allow.
- Interior Panelling ? The panels on your doors and sides may also be made from soft upholstery which is subject to constant wear and tear. A lot of common door panels are typically attached to the car by screws or easy-access clip systems, so determine if you can get these parts from your car dealer or auto shop.
DIY Upholstery Repair
Once you have determined the amount of work that needs to be done to your car, it?s time to get to work. Get all the tools you might need in order to perform the actual repair work; be it a screwdriver to remove interior panels, wrenches, cutters, and some strong adhesive to make sure the upholstery sticks to your car well. Here are some general step-by-step instructions to repairing your car upholstery:
- Lay out all the tools, replacement parts, and other things you need to get started on the upholstery repair. This can include snacks and drinks to keep your energy up when you take a break.
- Remove the things that need to be repaired from your car, if possible. This includes anything with upholstery that need fixing; your seats, door panels, carpets, and even your dashboard. This is to ensure nothing else in the car is damaged during the repair process. You can also try removing everything in your car except the thing that needs repairing.
- Once you have the part removed from the car, get side-by-side with your tools and start removing the upholstery from the part. This may take a little elbow grease and patience, even if you have the proper tools on hand already. If you are removing the seat covers from a car seat, also take note of where each and every part you remove came from, so installation may go smoother.
- If the upholstery you removed was held to the part by way of adhesives, then you may notice plenty of excess after removal. The excess adhesive will either already be very dry, or still sticky, depending on the kind of adhesive used. Try to remove all of the excess adhesive as best as you can before installing new upholstery.
- After removing the upholstery from a car, installation should be fairly straightforward with drop-in parts made for your car. If you are replacing upholstery that is not made for your car, or intended as a drop-in replacement, then more work may have to be done; you may have to apply adhesives to the newly-stripped part, apply the upholstery, and wait for it to dry.
When in doubt, call a car upholstery repair shop and have the work done for you instead.
rock center christine christine will ferrell double fine adventure turbo tax katharine mcphee
Sunday, April 1, 2012
The Texas Tribune: A Shortage of Rural Veterinarians Means Retirement Must Wait
in plain sight hunger games movie review bats hunger games review jeff saturday jason smith jon corzine